Easy Test for Visceral Leishmaniasis and Post–Kala-azar Dermal Leishmaniasis
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چکیده
1. Chai JY, Murrell KD, Lymbery AJ. Fishborne parasitic zoonoses: status and issues. Int J Parasitol. 2005;35:1233–54. doi:10.1016/j.ijpara.2005.07.013 2. Andrews RH, Sithithaworn P, Petney TN. Opisthorchis viverrini: an underestimated parasite in world health. Trends Parasitol. 2008;24:497–501. doi:10.1016/j. pt.2008.08.011 3. Parish RA. Intestinal parasites in Southeast Asian refugee children. West J Med. 1985;143:47–9. 4. Stich AH, Biays S, Odermatt P, Men C, Saem C, Sokha K, et al. Foci of Schistosoma mekongi, northern Cambodia: II. Distribution of infection and morbidity. Trop Med Int Health. 1999;4:674–85. doi:10.1046/j.1365-3156.1999.00474.x 5. Lee KJ, Bae YT, Kim DH, Deung YK, Ryang YS, Kim HJ, et al. Status of intestinal parasites infection among primary school children in Kampongcham, Cambodia. Korean J Parasitol. 2002;40:153–5. doi:10.3347/kjp.2002.40.3.153 6. Touch S, Komalamisra C, Radomyos P, Waikagul J. Discovery of Opisthorchis viverrini metacercariae in freshwater fi sh in southern Cambodia. Acta Trop. 2009;111:108–13. doi:10.1016/j. actatropica.2009.03.002 7. Chai JY, Park JH, Han ET, Guk SM, Shin EH, Lin A, et al. Mixed infections with Opisthorchis viverrini and intestinal fl ukes in residents of Vientiane Municipality and Saravane Province in Laos. J Helminthol. 2005;79:283–9. doi:10.1079/ JOH2005302 8. Rim HJ, Sohn WM, Yong TS, Eom KS, Chai JY, Min DY, et al. Fishborne trematode metacercariae detected in freshwater fi sh from Vientiane Municipality and Savannakhet Province, Lao PDR. Korean J Parasitol. 2008;46:253–60. doi:10.3347/ kjp.2008.46.4.253 9. Chai JY, Han ET, Shin EH, Sohn WM, Yong TS, Eom KS, et al. High prevalence of Haplorchis taichui, Prosthodendrium molenkampi, and other helminth infections among people in Khammouane Province, Lao PDR. Korean J Parasitol. 2009;47:243–7. doi:10.3347/ kjp.2009.47.3.243 10. Chai JY, Yong TS, Eom KS, Min DY, Shin EH, Banouvong V, et al. Prevalence of the intestinal fl ukes Haplorchis taichui and H. yokogawai in a mountainous area of Phongsaly Province, Lao PDR. Korean J Parasitol. 2010;48:339–42. doi:10.3347/ kjp.2010.48.4.339 Address for correspondence: Jong-Yil Chai, Department of Parasitology and Tropical Medicine, Seoul National University College of Medicine, Seoul 110-799, South Korea; email: [email protected]
منابع مشابه
DNA polymorphism assay distinguishes isolates of Leishmania donovani that cause kala-azar from those that cause post-kala-azar dermal Leishmaniasis in humans.
Leishmania donovani in India causes visceral infection (kala-azar) and dermal infection (post-kala-azar dermal leishmaniasis). We report here the identification of polymorphism in a well-defined genetic locus among the Leishmania parasites causing the visceral and dermal manifestations, in a comparison of 15 post-kala-azar dermal leishmaniasis and 12 kala-azar patient isolates.
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We assessed the prevalence of post-kala-azar dermal leishmaniasis (PKDL), a late cutaneous manifestation of visceral leishmaniasis (VL), in 16 VL-endemic communities in Bihar, India. The prevalence of confirmed PKDL cases was 4.4 per 10 000 individuals and 7.8 if probable cases were also considered. The clinical history and treatment of the post-kala-azar dermal leishmaniasis cases are discussed.
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In Brazil, visceral Leishmaniasis is caused by Leishmania chagasi. The development of cutaneous lesions in visceral leishmaniasis patients has been described in two different clinical contexts. Patients with compromised immunity can develop skin lesions as a direct consequence of a current visceral disease. Equally, patients with a history of kala-azar and progressive, immune improvement occasi...
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the patient had visceral leishmaniasis (kala-azar), successfully treated with 30 intramuscular injections of sodium stibogluconate (SSG). Polymerase chain reaction showed Leishmania donovani DNA in a buffy coat specimen. Post-kala-azar dermal leishmaniasis (PKDL) is a chronic skin rash usually seen in apparently cured kala-azar patients in East Africa and South Asia. In the Indian subcontinent,...
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Three patients who developed bilateral anterior uveitis at the end of, or soon after, the apparently successful treatment of visceral leishmaniasis are described. The uveitis gave rise to secondary glaucoma in 2 of the patients, and in the third patient the eye lesions were associated with an episode of post kala-azar dermal leishmaniasis.
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Post kala-azar dermal leishmaniasis (PKDL) is a dermatosis that occurs as a sequel of visceral leishmaniasis (VL). Elimination of VL requires detection and treatment of PKDL, necessarily because of its capacity to serve as a reservoir for the causative parasite, Leishmania donovani. Diagnosis of PKDL presents a challenge due to low parasite burden in the lesions. In this article we have reviewe...
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